Ixekizumab

Brand names: Taltz

An IL-17A inhibitor with strong effects on skin and joints.

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Ixekizumab
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Animated explainer

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How it works · Blocking IL-17
Immune cells release IL-17

IL-17 is a chemical messenger. Overactive immune cells release it to call in more inflammation.

What it’s used for

Psoriatic arthritis, axial spondyloarthritis and psoriasis.

How it works

It neutralizes IL-17A, a key inflammatory messenger in psoriatic disease.

How it’s taken

An injection under the skin every 4 weeks after starting doses.

Side effects

Injection-site reactions, infections and yeast infections. Rarely, inflammatory bowel disease.

Monitoring

TB screening, then clinical follow-up.

Good to know

Report new persistent diarrhea or abdominal pain.

At a glance

Class

Biologics

Brand names

Taltz

Reviewed by Farhan Tahir, MD, FACR

Questions about your own care?

Book an in-person or telehealth consultation with Dr. Tahir.

For education only. Don’t start, stop or change a medicine without talking to your care team.