All medications
Bone health
Alendronate
Brand names: Fosamax, Binosto
A widely used bisphosphonate that strengthens bone and lowers fracture risk.
Video lesson
Animated explainer
What it’s used for
Osteoporosis in women and men, and steroid-related bone loss.
How it works
It slows the osteoclasts that break down bone, letting bone-building catch up.
How it’s taken
A tablet once a week, first thing in the morning with a full glass of plain water. Stay upright and wait 30 minutes before food or other medicines.
Side effects
Heartburn and esophageal irritation if not taken correctly. Rarely, jaw bone problems or unusual thigh fractures after long use.
Monitoring
Bone density every 1 to 2 years, plus calcium and vitamin D levels.
Good to know
After 3 to 5 years your doctor may suggest a drug holiday based on your fracture risk.
At a glance
Class
Bone health
Brand names
Fosamax, Binosto
Reviewed by Farhan Tahir, MD, FACR
Questions about your own care?
Book an in-person or telehealth consultation with Dr. Tahir.
For education only. Don’t start, stop or change a medicine without talking to your care team.